Alpha-1 Antitrypsin Deficiency
Alpha-1 antitrypsin deficiency is a genetic disorder that may lead to liver and/or lung disease. It is a common cause of liver disease in children.
Symptoms
Diagnosis
Treatment
Symptoms
In babies, the symptoms of Alpha-1 antitrypsin deficiency include:
- Jaundice, a yellowing of the skin and eyes
- Abdominal swelling
- Poor feeding
In older children or adults, symptoms include:
- Jaundice, a yellowing of the skin and eyes
- Swelling of the legs and abdomen
- Fatigue
- Poor appetite
Diagnosing Alpha-1 antitrypsin deficiency
We will ask about your child’s medical history and symptoms. He or she will have a physical exam and may have additional tests:
Treating Alpha-1 antitrypsin deficiency
While there is no cure for Alpha-1, proper diet and vitamin supplements can maintain normal nutrition, and medication can provide relief from the symptoms. Is some cases, a liver transplant may be necessary.